Associate Principal Scientist, Vaccine Analytical R&D

Date: Jul 13, 2019

Location: West Point, PA, US

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Requisition ID: RES002265

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.

Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow, and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases. 

We are seeking an Associate Principal Scientist to join our Vaccine Analytical Research and Development team located in West Point, PA.  In this role, an individual will work with a team of scientists applying state of the art separation methods to facilitate vaccine development. 

The responsibilities of this role will be to lead and supervise a team of scientists applying capillary electrophoresis (CE) and other separation methods to support vaccine process development, formulation development, vaccine investigations, vaccine characterization, method qualifications and transfers.  

You will have strong analytical capabilities and experience with CE and liquid chromatography (LC). The candidate must also have experience with analysis of biological molecules and analytical method development and troubleshooting.  Previous experience working in a GMP environment, training and leading lab scientists, transferring and qualifying assays would also be directly applicable to this role.  You will be able to work both independently and in a team and have excellent communication and leadership skills.  You will be able to work and collaborate effectively in a multidisciplinary team environment and provide technical input to enable team decisions. Lastly, you will be expected to lead in authoring and reviewing scientific documents including development reports, analytical method protocols, qualification protocols, and electronic notebooks.


Education Minimum Requirement: 

A degree in Analytical Chemistry, Chemistry, Biochemistry, Pharmaceutical Science or a closely-related field plus industry experience is required: PhD with a minimum of 3 years post-degree experience OR Master’s with a minimum of 7 years post degree experience OR Bachelor’s with 10 years of experience.   

Required Experience and Skills: 

Experience training and leading junior scientists

Experience with CE, HPLC, UPLC

Experience with analysis of biological molecules.

Experience with analytical method development.

Ability to troubleshoot technical issues related to CE and chromatography methods.

Excellent verbal & written communication skills.

Capable of multi-tasking and managing multiple projects.

Motivated to learn new skills, willingness to take on new challenges, and scientific curiosity.

Preferred Experience and Skills:

Experience with Immuno-Assays.

Experience working in a GMP regulated environment.

Experience with method transfer.

Experience with assay robustness evaluation, method validation or qualification. 

Familiar with ICH guideline of analytical procedure validation.

Solid computer skills, experienced with automated laboratory instrumentation, and independent analytical problem-solving capabilities.

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life. 

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life. 


If you need assistance and/or a reasonable accommodation due to a disability during the application or the recruiting process, please send a request to


Search Firm Representatives Please Read Carefully: 

Merck & Co., Inc. is not accepting unsolicited assistance from search firms for this employment opportunity.  Please, no phone calls or emails.  All resumes submitted by search firms to any employee at Merck via email, the Internet or in any form and/or method without a valid written search agreement in place for this position will be deemed the sole property of Merck.  No fee will be paid in the event the candidate is hired by Merck as a result of the referral or through other means.


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Job: Research Science Generic
Other Locations:
Employee Status: Regular
Travel: No
Number of Openings: 1
Shift (if applicable): N/A
Hazardous Materials:
Company Trade Name: Merck

Nearest Major Market: Philadelphia

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