Senior Scientist, Discovery Pharmacogenomics

Date: Nov 27, 2018

Location: West Point, PA, US

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Requisition ID: INF004851

Merck & Co., Inc. is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. The difference between potential and achievement lies in the spark that fuels innovation and inventiveness; this is the space where Merck has codified its legacy for over a century. Merck’s success is backed by ethical integrity, forward momentum, and an inspiring mission to achieve new milestones in global healthcare.
Merck is on a quest for cures and is committed to being the world’s premier, most research-intensive biopharmaceutical company. Today, we’re doubling down on this goal. Merck Research Laboratories is a true scientific research facility of tomorrow and will take Merck’s leading discovery capabilities and world-class small molecule and biologics R&D expertise to create breakthrough science that radically changes the way we approach serious diseases. 
We are currently seeking a Senior Scientist data analyst to contribute to Merck’s genetic and genomic efforts in fighting infectious disease to decrease the overall burden of infection on global health. The Genetics and Pharmacogenomics Department (GpGx) is part of the larger Translational Medicine Department and has the unique opportunity to contribute to Discovery, Translational and Clinical Research. In this position, you will serve as a technical and scientific liaison to our renowned Vaccines and Infectious Disease research team, whose portfolio includes antibiotic and antifungal medicines, antiviral therapies for HIV and HCV, and both adult and pediatric vaccines. Your responsibilities will include:
  • Working collaboratively with the therapeutic area to apply cutting-edge genomic technologies and bioinformatics to identify novel drug targets, discover new biomarkers, and elucidate mechanisms of action to advance Infectious Disease programs
  • Participating in project team meetings to stay informed of program needs
  • Designing experiments and performing statistical and/or pathway and network analyses with a strong focus on biological interpretation and application to drug development
  • Communicating results to the program teams and therapeutic area leadership, spearheading both internal and peer-reviewed publications and presentations
  • Partnering within GpGx as well as with other internal and external stakeholders to effectively meet the needs of the Infectious Disease portfolio



Education Minimum Requirement:

  • Ph.D Degree with 1-3 years experience

Required Experience and Skills:

  • This is a non-wet lab position, so strong verbal and written communication skills and a solid background in the design, analysis and interpretation of data from genomic studies are necessities.
  • Experience with data analysis platforms such as MatLab, R, or OmicSoft is required.

Preferred Experience and Skills:

  • A background in Infectious Diseases (virology, microbiology and/or vaccinology), Immunology or Oncology is preferable, as the new hire will be asked to interface with one or all of these Therapeutic areas on a frequent basis.  
  • A working knowledge of systems biology, population genetics, and/or viral evolution will be viewed favorably, as will any experience in the design and analysis of experiments targeting the immune repertoire or microbiome.
  • Familiarity with drug discovery across multiple modalities (e.g., small molecule, biologic, cell-based therapy)

Your role at Merck is integral to helping the world meet new breakthroughs that affect generations to come, and we’re counting on your skills and inventiveness to help make meaningful contributions to global medical advancement. At Merck, we’re inventing for life. 


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Job: Informatics & Analytics
Other Locations: Boston, MA, US
Employee Status: Regular
Travel: Yes, 5 % of the Time
Number of Openings: 1
Shift (if applicable): 1st
Hazardous Materials: None
Company Trade Name: Merck

Nearest Major Market: Philadelphia

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