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Our journey for cutting-edge medicines for patients
The Genome and Biomarker Sciences (GBx) unit advances targets rooted in human genetics and genomics. We invest in innovative genomic and biomarker technologies for maximal pipeline impact. We leverage disease-relevant tissue samples to identify and apply genomic and protein biomarkers to inform clinical decision-making and exploratory research. Our goal is to translate the best human genetic targets into actionable biology.
Hear more about what drives our GBx employees each day
We operate 24/7 across:
Geographic regions:Asia Pacific, Europe, and North America
MSD sites, including all four discovery research hubs in Boston, Cambridge, London, and San Francisco
Human genetics helps to bring medications to life by leveraging:
Profiling and biomarkers
Data science and operations
GBx's interconnected functions collaborate to drive the discovery of clinical trial process forward:
Early Discovery Genetics and Genetics London – Leverages the power of human - validated genetic targets, large well-curated clinical trial datasets, and data derived from partnerships collected around the world
Genome Sciences – Establish and deploy functional genomics platforms to enable high-throughput biology
Discovery and Clinical Pharmacogenomics– Leverages high-through genetic and genomic technologies to discover and validate meaningful biomarkers
Integrated Operations – Provides operational excellence to efficiently execute on genomic biomarkers in all clinical trials
Profiling and Expression – Provides tissue-based analysis of human disease and model systems to enable mechanistic target validation, proof-of-activity and biomarker strategies
Oncology Genomics and Analytics – Apply analytics to pre-clinical and clinical oncology data
Translational Molecular Biomarkers – Develop, validate, and deploy biomarker assays for all therapeutic areas and all stages of clinical development
Pacific Translational Biomarkers – Develop and deploy molecular and imaging biomarkers to enable early clinical development or reverse translation; leverage Singapore external collaborations to advance our pipeline
Hear from our employees who help to save and improve lives every day
Our GBx department provides the continued focus on career development, opportunity for innovative contributions to our pipeline, and empowerment to be strategic leaders in the company.
Senior Principle Scientist, Genomics Policy
During my interview, I was immediately impressed by the amazing blend of scientific rigor, desire to help patients, and growth and mentorship opportunities that were present at this company. These key points are why I continue to enjoy coming to work every day and being a member of GBx and our company’s family.
Every day I am inspired by our scientific culture and strong drive to innovate therapeutics for our patients. In the GBx team we leverage cutting-edge genomic technologies and analytics to discover promising drug targets.
I love that in my role in GBx I get to keep up with cutting-edge science from academia and work towards leveraging these findings for future therapeutics.
Senior Scientist, Genome and Biomarker Sciences
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How we work
Our guiding principles
Leverage genomic, biomarkers, and tissue-based capabilities to impact drug discovery and program decision-making
Advance targets rooted in human genetics and genomics
Invest in innovative tools and technologies for maximal pipeline impact
Leverage disease-relevant tissue samples to identify and apply genetic, genomic and protein biomarkers to inform clinical decision making and exploratory research
Making GBx a great place to work
GBx fosters a positive, flexible workplace that is diverse, inclusive, and collaborative. Our organization supports colleagues through each phase of their careers, from onboarding to training and development and provides resources for working remotely, staying well, volunteering, and more. We are passionate about our people and offer programs to build future talent and help our employees grow and develop in their careers:
This careers website is intended for Residents of the United States, Canada & Puerto Rico. Residents in other markets, please visit our MSD Careers page. Information on this site is for the purpose of presenting career opportunities at our organization and give our audience a view of our culture, diversity and growth opportunities. Our Company is an equal opportunity employer, Minority/Female/Disability/Veteran, proudly embracing diversity in all of its manifestations.