Quantitative Pharmacology & Pharmacometrics (QP2)


Quantitative Pharmacology
​​​​​​​& Pharmacometrics (QP2)

Who we are


We translate breakthrough biomedical research into meaningful new therapies and vaccines that help improve and extend the lives of people worldwide. Through strengths in model-informed drug discovery/development, pharmacokinetics/pharmacodynamics, clinical pharmacology, biopharmaceutics, and regulatory acumen we aim to advance high-quality, differentiated programs in the most streamlined path to registration in collaboration with our partners.

Worldwide operations


The department is made up of over 50 quantitative scientists with the majority distributed between West Point, PA and Rahway, NJ. Co-location with our key discovery and development partners enables us to deliver on our purpose while flexible work arrangements enable our group to balance work and life.
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Our organization


The department has groups aligned to therapeutic areas (TAs) that create deeper understanding in TA biology, relevant clinical endpoints, patient populations, and the competitive landscape. This allows us to optimally tailor our quantitative contributions to drive impact. In addition, a dedicated pharmacometrics group harbors deep modeling and simulation expertise and focuses on applying state-of-the-art quantitative approaches.

What we do

QP2 aims to deliver significant value through optimizing dosage, identifying opportunities to halt development of undifferentiated assets, and streamlining the development of promising compounds and biologics, all of which contribute to life-changing therapies for patients. Our core strength has been in the areas of dose selection and characterization of pharmacokinetic (PK) and pharmacodynamic (PD) properties, while we continue to grow our strategy in areas such as informing the feasibility of targets in discovery, growing the impact of modeling in vaccine development, and investing in advanced data science capabilities to enable the use of digital and real-world data.

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Our story by the numbers

We embrace a dynamic, diverse, and inclusive workforce:
50+
Scientists
10+
Educational backgrounds
15
Countries represented
1:1
Female-to-male ratio
​​​​​​​including leadership

Hear from our employees who innovate every day

I am energized and gratified by the breadth and depth of QP2’s impact on MRL portfolio decisions from discovery through life-cycle management across multiple therapeutic areas and modalities. I am proud to lead a team of highly talented and motivated quantitative scientists who thrive on innovative science and challenging the status quo.
Ann Houseman
Prajakti Kothare
Associate Vice President
At our company, we focus on patient safety and health, drive a culture of trust and togetherness, emphasize scientific excellence, and most importantly, make a difference in people’s lives every day. Within the Quantitative Pharmacology and Pharmacometrics group, we strive to use mathematical reasoning to validate, facilitate, and accelerate our decision-making while aligning with our company vision. 
Yash Kapoor
Principal Scientist
I’m proud to work for a group that not only values the work we do every day but also invests in the development of employees by providing unlimited learning & development opportunities within the organization. The culture of providing real-time feedback and recognition allows us to evaluate performance in real-time and to provide early course correction.
Mayank Patel
Principal Scientist
I love being at our company because of the cutting-edge research that is done here. I know the work I do is helping bring drugs and vaccines to patients that need them.
Brian Maas
Principal Scientist
I find QP2 a collaborative, inspiring, and inclusive team where talented people with diverse backgrounds focus on portfolio, brainstorm scientific plans, and impact program decisions. I really enjoy and am passionate about using data science,modeling, and simulation to inform dosing selection and PKPD properties of novel drugs, which QP2 significantly values.
Shuai Hu
Senior Scientist
I belong to a group with broad expertise and diverse backgrounds. I feel inspired every day by our innovations in developing therapeutics for various diseases and the benefits we bring to patients.
Dan Li
Associate Principal Scientist
At our company, we foster a diverse and inclusive culture in science and community. I’m proud to be part of a group that is committed to accelerating the availability of innovative therapies for patients using quantitative methods.
Xiaowei Zang
Associate Principal Scientist

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This careers website is intended for Residents of the United States, Canada & Puerto Rico. Residents in other markets, please visit our MSD Careers page. Information on this site is for the purpose of presenting career opportunities at our organization and give our audience a view of our culture, diversity and growth opportunities. Our Company is an equal opportunity employer, Minority/Female/Disability/Veteran, proudly embracing diversity in all of its manifestations.